Deforolimus
产品编号: DC9514
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应用领域
Deforolimus (AP23573; MK-8669) 是一种有效和选择性的 mTOR 抑制剂，在 HT-1080 细胞中抑制 S6磷酸化的 IC50 值为 0.2 nM。
| Cas No.: |
572924-54-0 |
| 名称: |
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| 别名: |
AP23573; MK-8669; Ridaforolimus; AP 23573; MK 8669; AP-23573; MK8669 |
| SMILES: |
C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C\[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OP(=O)(C)C)C)/C)O)OC)C)C)/C)OC |
| 分子式: |
C53H84NO14P |
| 分子量: |
990.2061 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
Deforolimus(AP23573; MK-8669; Ridaforolimus) is a selective mTOR inhibitor with IC50 of 0.2 nM; while not classified as a prodrug, mTOR inhibition and FKBP12 binding is similar to rapamycin.
in vitro: Treatment of HT-1080 cells with Deforolimus induces a |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_2660_DC9514_572924-54-0 |
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DOWNLOAD |
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询盘
