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Fexaramine

产品编号: DC8085 Featured
Fexaramine
结构式
574013-66-4
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中国地区超过5000个高品质化合物库存
应用领域
Fexaramine是FXR受体小分子激动剂。
Cas No.: 574013-66-4
名称: 3-[3-[(Cyclohexylcarbonyl)-[[4'-(dimethylamino)-[1,1'-biphenyl]-4-yl]methyl]amino]phenyl]-2-propenoicacidmethylester
别名: Fexaramine
SMILES: CN(C)C1=CC=C(C=C1)C2=CC=C(C=C2)CN(C3=CC=CC(=C3)/C=C/C(=O)OC)C(=O)C4CCCCC4
分子式: C32H36N2O3
分子量: 496.64
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Fexaramine is a potent, selective FXR (farnesoid X receptor) agonist (EC50 = 25 nM). Fexaramine displays no activity at hRXRα, hPPARα, hPPARγ, hPPARδ, mPXR, hPXR, hLXRα, hTRβ, hRARβ, mCAR, mERRγ and hVDR receptors. For the detailed information of Fexaramine, the solubility of Fexaramine in water, the solubility of Fexaramine in DMSO, the solubility of Fexaramine in PBS buffer, the animal experiment (test) of Fexaramine, the cell expriment (test) of Fexaramine, the in vivo, in vitro and clinical trial test of Fexaramine, the EC50, IC50,and affinity,of Fexaramine, For the detailed information of Fexaramine, the solubility of Fexaramine in water, the solubility of Fexaramine in DMSO, the solubility of Fexaramine in PBS buffer, the animal experiment (test) of Fexaramine, the cell expriment (test) of Fexaramine, the in vivo, in vitro and clinical trial test of Fexaramine, the EC50, IC50,and affinity,of Fexaramine, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
TITLE DOWNLOAD
MSDS_2127_DC8085_574013-66-4
COA
LOT NO. DOWNLOAD
产品编号 产品名称 应用领域
DC8085 Fexaramine Fexaramine是FXR受体小分子激动剂。
DC8071 Fexarine Fexarine is a potent, selective farnesoid X receptor agonist.
DC8070 Fexarene Fexarene is a potent, selective farnesoid X receptor agonist.
DC8069 Fexaramate Fexaramate is a potent, selective farnesoid X receptor agonist.
DC7566 GW-4064 GW 4064 是一种有效的 FXR 激动剂,EC50 为 65 nM。
DC10470 SB756050 SB756050 是选择性的 TGR5 激动剂。SB756050有潜力用于二型糖尿病的研究。