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BIO-acetoxime

产品编号: DC8368 Featured
BIO-acetoxime
结构式
667463-85-6
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中国地区超过5000个高品质化合物库存
应用领域
BIO-acetoxime (BIA) 是一种有效、选择性的 GSK-3 抑制剂，对 GSK-3α/β 的 IC50 值均为 10 nM；BIO-acetoxime 具有抗惊厥和抗感染作用。
化学性质生物活性化合物的使用COA & MSDS相关产品产品说明书
Cas No.: 667463-85-6
名称: (2'Z,3'E)-6-Bromoindirubin-3'-acetoxime
别名:
SMILES: CC(=O)O/N=C1\C2C=CC=CC=2N\C\1=C1/C2C=CC(=CC=2NC/1=O)Br
分子式: C18H12BrN3O3
分子量: 398.21
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: BIO-Acetoxime is an analog of the GSK3 inhibitor 6-bromoindirubin-3’-oxime, or BIO.It potently inhibits GSK3α/β (IC50 = 10 nM), with selectivity over Cdk5/p25, Cdk2/A, and Cdk1/B (IC50s = 2.4, 4.3, and 63 µM, respectively).BIO-Acetoxime has been used to study the role of GSK3 in the Wnt/β-catenin pathway.3 It also suppresses the cytopathic effects of herpes viruses and reduces viral yields in human oral epithelial cells. For the detailed information of BIO-Acetoxime, the solubility of BIO-Acetoxime in water, the solubility of BIO-Acetoxime in DMSO, the solubility of BIO-Acetoxime in PBS buffer, the animal experiment (test) of BIO-Acetoxime, the cell expriment (test) of BIO-Acetoxime, the in vivo, in vitro and clinical trial test of BIO-Acetoxime, the EC50, IC50,and affinity,of BIO-Acetoxime, For the detailed information of BIO-Acetoxime, the solubility of BIO-Acetoxime in water, the solubility of BIO-Acetoxime in DMSO, the solubility of BIO-Acetoxime in PBS buffer, the animal experiment (test) of BIO-Acetoxime, the cell expriment (test) of BIO-Acetoxime, the in vivo, in vitro and clinical trial test of BIO-Acetoxime, the EC50, IC50,and affinity,of BIO-Acetoxime, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
TITLE DOWNLOAD
MSDS_2309_DC8368_667463-85-6
COA
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