PF-562271
产品编号: DC3169
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应用领域
PF-562271 是有效，可逆，ATP竞争性的 FAK 和 Pyk2 激酶抑制剂，IC50 分别为 1.5 和 13 nM。
| Cas No.: |
717907-75-0 |
| 名称: |
Methanesulfonamide, N-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl- |
| 别名: |
PF562271,PF 562271 |
| SMILES: |
CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C |
| 分子式: |
C21H20F3N7O3S |
| 分子量: |
507.49 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
Description of PF-562271: PF-562271 is an orally bioavailable small molecule and ATP-competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities. FAK inhibitor PF-00562271 inhibits the tyrosine kinase FAK, |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1345_DC3169_717907-75-0 |
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COA
| LOT NO. |
DOWNLOAD |
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