Luminespib (NVP-AUY922)
产品编号: DC5202
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应用领域
Luminespib (NVP-AUY922) 是有效的 HSP90 抑制剂，抑制 HSP90α 和 HSP90β 的 IC50 分别为 7.8 和 21 nM。
| Cas No.: |
747412-49-3 |
| 名称: |
5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide |
| 别名: |
AUY 922,AUY-922, NVP-AUY922，NVP-AUY922-NX，AUY922,VER-52296 |
| SMILES: |
O1C(C2=CC(C(C)C)=C(O)C=C2O)=C(C2=CC=C(CN3CCOCC3)C=C2)C(C(NCC)=O)=N1 |
| 分子式: |
C26H31N3O5 |
| 分子量: |
465.54 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
In vitro:NVP-AUY922 inhibits proliferation of various human cancer cell lines in vitro, with an average GI50 of 9 nM. The IC50 values of NVP-AUY922 fall in the range of 2 to 40 nM in these gastric cancer cell lines. IC50 value For the BEAS-2B cells is 28 |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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