Dinaciclib (SCH727965)
产品编号: DC7114
我们的合作伙伴:
中国地区超过5000个高品质化合物库存
应用领域
Dinaciclib (SCH727965) is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM, respectively.
| Cas No.: |
779353-01-4 |
| 名称: |
2-[(2S)-1-[3-ethyl-7-[(1-oxidopyridin-1-ium-3-yl)methylamino]pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-2-yl]ethanol |
| 别名: |
SCH 727965; SCH727965; SCH-727965 |
| SMILES: |
OCC[C@H]1N(CCCC1)C2=NC3=C(C=NN3C(NCC4=C[N+]([O-])=CC=C4)=C2)CC |
| 分子式: |
C21H28N6O2 |
| 分子量: |
396.49 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
Dinaciclib is also a potent DNA replication inhibitor that blocks thymidine (dThd) DNA incorporation in A2780 cells with IC50 of 4 nM. Dinaciclib strongly suppresses phosphorylation of Rb on Ser 807/811 at concentrations >6.25 nM, which is in agreement wi |
| Kinase Assay: |
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| Animal Administration: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_3407_DC7114_779353-01-4 |
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COA
| LOT NO. |
DOWNLOAD |
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