PHA-739358 (danusertib)
产品编号: DC4125
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应用领域
Danusertib 是一种极光激酶 (aurora kinase) 抑制剂，能够抑制 Aurora A，Aurora B 和 Aurora C 的活性，IC50 值分别为 13，79 和 61 nM。
| Cas No.: |
827318-97-8 |
| 名称: |
(R)-N-(5-(2-methoxy-2-phenylacetyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-4-(4-methylpiperazin-1-yl)benzamide |
| 别名: |
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| SMILES: |
CN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3=NNC4=C3CN(C4)C(=O)[C@@H](C5=CC=CC=C5)OC |
| 分子式: |
C26H30N6O3 |
| 分子量: |
474.55 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
Description of Danusertib: Danusertib is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity. Aurora kinase inhibitor PHA-739358 binds to and inhibits the Aurora kinases, which may result in cell growth arrest and apoptosis |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1361_DC4125_827318-97-8 |
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COA
| LOT NO. |
DOWNLOAD |
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