SW076956

产品编号: DC10965
SW076956
结构式
851717-83-4
此产品仅供科研所需,我们不出售给病人
​我们将匹配市场上最好的价格给您
Email:order@dcbio.cn
免费咨询电话:4008862077
我们的合作伙伴:
  • 20
  • 19
  • 18
  • 17
  • 16
  • 15
  • 14
  • 12
  • 11
  • 10
  • 9
  • 8
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
中国地区超过5000个高品质化合物库存
应用领域
SW076956是一种小分子,与Bax/Bcl-2和Bim/Bcl-2结合相比,选择性地破坏Beclin 1/Bcl-2结合,并在具有最小细胞毒性的浓度下诱导自噬通量。
Cas No.: 851717-83-4
名称: N-(4-(5-(furan-2-yl)-1-(4-methylbenzoyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
别名: SW-076956,SW 076956
SMILES: CS(NC1=CC=C(C2CC(C3=CC=CO3)N(C(=O)C3=CC=C(C)C=C3)N=2)C=C1)(=O)=O
分子式: C22H21N3O4S
分子量: 423.487
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: SW076956 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC9296 A-1331852 A-1331852 is a high affinity BH3 mimetic Ligand of BCL protein BCL-XL.
DC8444 Sabutoclax Sabutoclax(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.
DC5005 tw-37 TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 μM, 1.11 μM and 0.26 μM, respectively.
DC10965 SW076956 SW076956是一种小分子,与Bax/Bcl-2和Bim/Bcl-2结合相比,选择性地破坏Beclin 1/Bcl-2结合,并在具有最小细胞毒性的浓度下诱导自噬通量。