DL-AP7

产品编号: DC9250 Featured
DL-AP7
结构式
85797-13-3
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中国地区超过5000个高品质化合物库存
应用领域
DL-AP7 is a competitive antagonist of the ionotropic glutamate receptor, NMDA.
Cas No.: 85797-13-3
名称: DL-2-Amino-7-phosphonoheptanoic acid
别名:
SMILES: C(CCC(C(=O)O)N)CCP(=O)(O)O
分子式: C7H16NO5P
分子量: 225.2
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: DL-AP7 is a competitive antagonist of the ionotropic glutamate receptor, NMDA. Studies indicate that the S1 and S2 domains of the NMDA receptor are essential in DL-AP7 and other related antagonists to bind to the receptor. In addition, the positively charged Lys residues at the second interaction site and Arg at the fourth site are key factors in ligand binding. The NMDA receptor is unique in that it requires binding of two ligands, glutamate and glycine to become activated. As a result of its inhibitory affects, DL-AP7 is an ideal tool in studying signaling pathways and ion flow through the NMDA receptor.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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