| Cas No.: | 860352-01-8 |
| 名称: | 1-(2-((S)-piperidin-3-ylcarbamoyl)-5-(3-fluorophenyl)thiophen-3-yl)urea |
| 别名: | AZD7762; AZD-7762 |
| SMILES: | N(C1C=C(C2=CC=CC(F)=C2)SC=1C(=O)N[C@@H]1CCCNC1)C(N)=O |
| 分子式: | C17H19FN4O2S.HCl |
| 分子量: | 398.889 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | AZD7762, a more selective Chk1 inhibitor, inhibits Chk1 phosphorylation of a cdc25C peptide by reversibly binding to the ATP-binding site of Chk1, with IC50 of 5 nM and Ki of 3.6 nM. AZD7762 induces cell arrest with EC50 of 0.620 μM, and significantly abr |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
| TITLE | DOWNLOAD |
| MSDS_1536_DC7076_860352-01-8 |
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COA
| LOT NO. | DOWNLOAD |
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