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AMG 837 is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents.
| Cas No.: |
865231-46-5 |
| 名称: |
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| 别名: |
AMG-837; AMG837 |
| SMILES: |
OC(C[C@H](C#CC)C1=CC=C(C=C1)OCC2=CC=CC(C3=CC=C(C(F)(F)F)C=C3)=C2)=O |
| 分子式: |
C26H21F3O3 |
| 分子量: |
438.44 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
AMG 837 is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents.
IC50 value: 13 nM (EC50)
Target: GPR40 agonist
AMG 837 displayed the expected two-fold increas |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_3460_DC7867_865231-46-5 |
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COA
| LOT NO. |
DOWNLOAD |
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