AF-353(Ro-4)
产品编号: DC7783
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应用领域
AF-353 (Ro-4) 是一种有效选择性、口服可利用的 P2X3/P2X2/3 受体拮抗剂, 抑制人和大鼠 P2X3 的 pIC50 值为 8.0，抑制人 P2X2/3 的 pIC50 值为 7.3。
| Cas No.: |
865305-30-2 |
| 名称: |
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| 别名: |
CHEMBL526307,AF 353,AF353 |
| SMILES: |
CC(C)C1=CC(=C(C=C1OC2=CN=C(N=C2N)N)I)OC |
| 分子式: |
C14H17In4O2 |
| 分子量: |
400.21 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
AF-353 is a potent antagonist of P2X3 homotrimers and P2X2/3 heterotrimers with a pIC50 range of 7.3 - 8.5. The compound does not affect other P2X family members at 300-fold excess concentrations. AF. For the detailed information of AF-353, the solubility |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
