Anacetrapib(MK0859)
产品编号: DC7804
Featured
我们的合作伙伴:
中国地区超过5000个高品质化合物库存
应用领域
Anacetrapib 是一种有效的 CETP 抑制剂，作用于 rhCETP 和 C13S CETP 突变型，IC50 分别为 7.9±2.5 nM 和 11.8±1.9 nM。
| Cas No.: |
875446-37-0 |
| 名称: |
|
| 别名: |
MK-0859, MK 0859, MK0859 |
| SMILES: |
O1[C@@H](C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)[C@@H](C)N(CC2=CC(C(F)(F)F)=CC=C2C2=CC(C(C)C)=C(F)C=C2OC)C1=O |
| 分子式: |
C30H25F10NO3 |
| 分子量: |
637.51 |
| 纯度: |
|
| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
|
| In Vivo: |
|
| In Vitro: |
|
| References: |
Anacetrapib is not only able to increase HDL-cholesterol, but also further decreases LDL-cholesterol when taken in combination with a statin. Anacetrapib dose-dependently and significantly decreases the transfer of CE from HDL3 to HDL2. Anacetrapib doesn' |
| Kinase Assay: |
|
| Cell Assay: |
|
| Animal Administration: |
|
| References: |
|
MSDS
COA
| LOT NO. |
DOWNLOAD |
|
|
| 2018-0101 |
|
询盘
