LY2119620

产品编号: DC8435
LY2119620
结构式
886047-22-9
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中国地区超过5000个高品质化合物库存
应用领域
LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.
Cas No.: 886047-22-9
名称: 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methyl-1-piperazinyl)-2-oxoethoxy]-thieno[2,3-b]pyridine-2-carboxamide
别名: LY2119620,LY-2119620,LY 2119620
SMILES: CN1CCN(C(COC2=C(Cl)C(C)=C3C(SC(C(NC4CC4)=O)=C3N)=N2)=O)CC1
分子式: C19H24ClN5O3S
分子量: 437.94
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: LY2119620 displays modest allosteric agonism and positively modulates the functional G protein–signaling ability of an agonist at the M2/M4 receptor subtypes by placing the M2 and M4 receptors into an active G protein–bound state. LY2119620 enhances the potency of three muscarinic acetylcholine receptor agonists, ACh, Oxo-M and iperoxo. [3H]LY2119620 can be used as a probe for the human M(2) and M(4) muscarinic receptor allosteric binding sites. For the detailed information of LY2119620, the solubility of LY2119620 in water, the solubility of LY2119620 in DMSO, the solubility of LY2119620 in PBS buffer, the animal experiment (test) of LY2119620, the cell expriment (test) of LY2119620, the in vivo, in vitro and clinical trial test of LY2119620, the EC50, IC50,and affinity,of LY2119620, For the detailed information of LY2119620, the solubility of LY2119620 in water, the solubility of LY2119620 in DMSO, the solubility of LY2119620 in PBS buffer, the animal experiment (test) of LY2119620, the cell expriment (test) of LY2119620, the in vivo, in vitro and clinical trial test of LY2119620, the EC50, IC50,and affinity,of LY2119620, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC8435 LY2119620 LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.