MK-8776 (SCH 900776)
产品编号: DC5024
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应用领域
SCH900776 是一种有效，选择性，可口服的 Chk1 抑制剂，IC50 值为 3 nM；它比对CDK2 和 Chk2 的选择性分别高50和500倍。
| Cas No.: |
891494-63-6 |
| 名称: |
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| 别名: |
SCH-900776; SCH 900776, MK-8776. |
| SMILES: |
C12=C(C3=CN(C)N=C3)C=NN1C(N)=C(Br)C([C@H]1CCCNC1)=N2 |
| 分子式: |
C15H18BrN7 |
| 分子量: |
376.25 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
SCH900776, also known as MK-8776. is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities. Chk1 inhibitor SCH 900776 specifically binds to and inhibits Chk1, which may result in tum |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
