MF63
产品编号: DC7651
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应用领域
MF63是mPGES-1抑制剂,对猪mPGES-1和人mPGES-1的IC50分别为0.9 nM和1.3 nM。
| Cas No.: |
892549-43-8 |
| 名称: |
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| 别名: |
MF 63; MF-63 |
| SMILES: |
C1=CC=C2C(=C1)C3=C(C=CC(=C3)Cl)C4=C2N=C(N4)C5=C(C=CC=C5C#N)C#N |
| 分子式: |
C23H11ClN4 |
| 分子量: |
378.81 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
MF63 is a selective mPGES-1 inhibitor with an IC50 of 0.9 nM and 1.3 nM For pig mPGES-1 and human mPGES-1 enzyme, respectively. MF63 potently inhibited the human mPGES-1 enzyme with a high degree (>1000-fold) of selectivity over other prostanoid synthase |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1875_DC7651_892549-43-8 |
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COA
| LOT NO. |
DOWNLOAD |
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