PF-2545920(MP-10)
产品编号: DC7201
Featured
我们的合作伙伴:
中国地区超过5000个高品质化合物库存
应用领域
Mardepodect (PF-2545920) 是一种有效的，口服活性的，选择性的 PDE10A 抑制剂，IC50 为 0.37 nM，比作用于其他 PDE 选择性高 1000 多倍。Mardepodect 可穿过血脑屏障。
| Cas No.: |
898562-94-2 |
| 名称: |
2-((4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)phenoxy)methyl)quinoline |
| 别名: |
PF 2545920; PF2545920,MP10,MP 10 |
| SMILES: |
CN1C=C(C(=N1)C2=CC=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)C5=CC=NC=C5 |
| 分子式: |
C25H20N4O |
| 分子量: |
392.45 |
| 纯度: |
|
| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
|
| In Vivo: |
|
| In Vitro: |
|
| References: |
PF-2545920(MP-10) shows excellent potency and selectivity of PDE10A with IC50 of 1.26 nM. MP-10 intraperitoneally administrated at dose of 0.3, 3, and 5 mg/kg in male CF-1 mice causes striking increases in GluR1 phosphorylation levels of 3-, 5.4-, and 4.1 |
| Kinase Assay: |
|
| Cell Assay: |
|
| Animal Administration: |
|
| References: |
|
MSDS
| TITLE |
DOWNLOAD |
| MSDS_1620_DC7201_898562-94-2 |
|
COA
| LOT NO. |
DOWNLOAD |
|
|
询盘
