T-00127-HEV1

产品编号: DC8063 Featured
T-00127-HEV1
结构式
900874-91-1
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中国地区超过5000个高品质化合物库存
应用领域
T-00127_HEV1 是一个 phosphatidylinositol 4-kinase III beta (PI4KB) 抑制剂,其 IC50 值为 60 nM。
Cas No.: 900874-91-1
名称: 3-(3,4-Dimethoxyphenyl)-2,5-dimethyl-N-[2-(4-morpholinyl)ethyl]-pyrazolo[1,5-a]pyrimidin-7-amine
别名: T00127-HEV1,T 00127 HEV1
SMILES: CC1=NC2=C(C(=NN2C(=C1)NCCN3CCOCC3)C)C4=CC(=C(C=C4)OC)OC
分子式: C22H29N5O3
分子量: 411.5
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: T-00127-HEV1 inhibited PI4KB activity with a higher specificity for than other PI kinases, in contrast to GW5074, which had a broad specificity for PI . T-00127-HEV1 and GW5074 did not inhibit hepatitis C virus (HCV) replication, in contrast to a strong inhibitory effect of AN-12-H5. PI4KB is an enterovirus-specific host factor required for the replication process and targeted by some enviroxime-like compounds (T-00127-HEV1 and GW5074) and that enviroxime-like compounds may have targets other than PI kinases for their antiviral effect. For the detailed information of T-00127-HEV1, the solubility of T-00127-HEV1 in water, the solubility of T-00127-HEV1 in DMSO, the solubility of T-00127-HEV1 in PBS buffer, the animal experiment (test) of T-00127-HEV1, the cell expriment (test) of T-00127-HEV1, the in vivo, in vitro and clinical trial test of T-00127-HEV1, the EC50, IC50,and affinity,of T-00127-HEV1, For the detailed information of T-00127-HEV1, the solubility of T-00127-HEV1 in water, the solubility of T-00127-HEV1 in DMSO, the solubility of T-00127-HEV1 in PBS buffer, the animal experiment (test) of T-00127-HEV1, the cell expriment (test) of T-00127-HEV1, the in vivo, in vitro and clinical trial test of T-00127-HEV1, the EC50, IC50,and affinity,of T-00127-HEV1, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC8063 T-00127-HEV1 T-00127_HEV1 是一个 phosphatidylinositol 4-kinase III beta (PI4KB) 抑制剂,其 IC50 值为 60 nM。