| Cas No.: | 910232-84-7 |
| 名称: | 4-(tert-butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morpholine-4-carbonyl)phenyl)amino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide |
| 别名: | CGI1746,CGI-1746,CGI 1746 |
| SMILES: | C(NC1=CC=CC(C2N=C(NC3=CC=C(C(N4CCOCC4)=O)C=C3)C(=O)N(C)C=2)=C1C)(=O)C1=CC=C(C(C)(C)C)C=C1 |
| 分子式: | C34H37N5O4 |
| 分子量: | 579.69 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
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| In Vitro: | |
| References: | CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for e |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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