LY2603618(IC-83)
产品编号: DC7103
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应用领域
Rabusertib (LY2603618) 是一种有效的选择性的 Chk1 抑制剂，IC50 为 7 nM。
| Cas No.: |
911222-45-2 |
| 名称: |
(S)-1-(5-bromo-4-methyl-2-(morpholin-2-ylmethoxy)phenyl)-3-(5-methylpyrazin-2-yl)urea |
| 别名: |
IC-83; LY 2603618; LY-2603618 |
| SMILES: |
CC1=CC(=C(C=C1Br)NC(=O)NC2=NC=C(N=C2)C)OC[C@@H]3CNCCO3 |
| 分子式: |
C18H22BrN5O3 |
| 分子量: |
436.3 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
Chk1 is an ATP-dependent serine-threonine kinase and a key component in the DNA replication-monitoring checkpoint system activated by double-stranded breaks (DSBs). Chk1 contributes to all currently defined cell cycle checkpoints, including G1/S, intra-S- |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
