Guadecitabine(SGI-110)
产品编号: DC6313
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应用领域
Guadecitabine (SGI-110) 是 DNA 甲基转移酶 (DNMT) 的抑制剂。
| Cas No.: |
929901-49-5 |
| 名称: |
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| 别名: |
SGI110,SGI 110 |
| SMILES: |
O=C1C2=C(N([C@H]3C[C@H](O)[C@@H](COP(O)(O[C@@H]4[C@@H](CO)O[C@@H](N5C=NC(N)=NC5=O)C4)=O)O3)C=N2)NC(N)=N1 |
| 分子式: |
C18H23N9NaO10P |
| 分子量: |
579.39 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
SGI-110 is a 5-aza-2’-deoxycytidine-containing demethylating dinucleotide, which works via a mechanism similar to that of 5-aza-CdR after incorporation of its aza-moiety into DNA. However, SGI-110 is well protected from deamination by cytidine deaminase. |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1487_DC6313_929901-49-5 |
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COA
| LOT NO. |
DOWNLOAD |
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