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AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM, selectivity against JAK3 and Tyk2, and to a smaller extent against JAK1. Phase 1/2.
| Cas No.: |
935666-88-9 |
| 名称: |
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| 别名: |
AZD 1480,AZD-1480 |
| SMILES: |
CC1=CC(=NN1)NC2=NC(=NC=C2Cl)N[C@@H](C)C3=NC=C(C=N3)F |
| 分子式: |
C14H14ClFN8 |
| 分子量: |
348.77 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM, selectivity against JAK3 and Tyk2, and to a smaller extent against JAK1.
IC50 value: 0.26 nM
Target: JAK2
in vitro: AZD1480 demonstrated significant immunoregulatory effects by downr |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_3385_DC5032_935666-88-9 |
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COA
| LOT NO. |
DOWNLOAD |
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