OSI-027

产品编号: DC1006
OSI-027
结构式
936890-98-1
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中国地区超过5000个高品质化合物库存
应用领域
OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, respectively.
Cas No.: 936890-98-1
名称: (1r,4r)-4-(4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[1,5-f][1,2,4]triazin-7-yl)cyclohexanecarboxylic acid
别名: OSI027,OSI 027
SMILES: O=C([C@H]1CC[C@H](C2=NC(C(N3)=CC4=C3C(OC)=CC=C4)=C5C(N)=NC=NN52)CC1)O
分子式: C21H22N6O3
分子量: 406.44
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: A potent, selective and orally bioavailable mTOR inhibitor currently in clinical trial. For the detailed information about the solubility of OSI-027 in water, the solubility of OSI-027 in DMSO, the solubility of OSI-027 in PBS buffer, the animal experiment(test) of OSI-027,the in vivo,in vitro and clinical trial test of OSI-027,the cell experiment(test) of OSI-027,the IC50, EC50 and Affinity of OSI-027, please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC1006 OSI-027 OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, respectively.