NSC95397
产品编号: DC11691
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应用领域
A potent, selective, reversible Cdc25 dual specificity phosphatase inhibitor with Ki of 32/96/40 nM for Cdc25A/B/C, respectively.
| Cas No.: |
93718-83-3 |
| 名称: |
2,3-bis[(2-Hydroxyethyl)thiol]-1,4-naphthoquinone |
| 别名: |
NSC-95397;NSC 95397 |
| SMILES: |
C1=CC=C2C(=C1)C(=O)C(=C(C2=O)SCCO)SCCO |
| 分子式: |
C14H14O4S2 |
| 分子量: |
310.38 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
A potent, selective, reversible Cdc25 dual specificity phosphatase inhibitor with Ki of 32/96/40 nM for Cdc25A/B/C, respectively; displays 125- and 180-fold selectivity over VH1-related dual-specificity phosphatase and PTP1B; shows significant growth inhibition in cancer cells and blocks G(2)/M phase transition; also inhibits cellular MKP-1 and MKP-3 with IC50 of 13 uM. |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
