NSC95397

产品编号: DC11691 Featured
NSC95397
结构式
93718-83-3
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中国地区超过5000个高品质化合物库存
应用领域
A potent, selective, reversible Cdc25 dual specificity phosphatase inhibitor with Ki of 32/96/40 nM for Cdc25A/B/C, respectively.
Cas No.: 93718-83-3
名称: 2,3-bis[(2-Hydroxyethyl)thiol]-1,4-naphthoquinone
别名: NSC-95397;NSC 95397
SMILES: C1=CC=C2C(=C1)C(=O)C(=C(C2=O)SCCO)SCCO
分子式: C14H14O4S2
分子量: 310.38
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: A potent, selective, reversible Cdc25 dual specificity phosphatase inhibitor with Ki of 32/96/40 nM for Cdc25A/B/C, respectively; displays 125- and 180-fold selectivity over VH1-related dual-specificity phosphatase and PTP1B; shows significant growth inhibition in cancer cells and blocks G(2)/M phase transition; also inhibits cellular MKP-1 and MKP-3 with IC50 of 13 uM.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC11691 NSC95397 A potent, selective, reversible Cdc25 dual specificity phosphatase inhibitor with Ki of 32/96/40 nM for Cdc25A/B/C, respectively.