| Cas No.: | 942918-07-2 |
| 名称: | 3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea |
| 别名: | GSK1070916,GSK-1070916,GSK 1070916 |
| SMILES: | N(C)(C)C(NC1=CC=C(C2C(C3C=CN=C4NC(C5=CC=CC(CN(C)C)=C5)=CC4=3)=CN(CC)N=2)C=C1)=O |
| 分子式: | C30H33N7O |
| 分子量: | 507.63 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | GSK1070916 selectively inhibits Aurora B and Aurora C with Ki of 0.38 nM and 1.5 nM over Aurora A with Ki of 490 nM. Inhibition of Aurora B and Aurora C is time-dependent, with an enzyme-inhibitor dissociation half-life of >480 min and 270 min respectivel |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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