| Cas No.: | 1072959-67-1 |
| 名称: | N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl-2,3-dihydro-1,4-benzodioxin-2-carboxamidedihydrochloride |
| 别名: | SR-3677; SR 3677 |
| SMILES: | CN(C)CCOC1=C(NC(C2OC(C=CC=C3)=C3OC2)=O)C=CC(C4=CNN=C4)=C1 |
| 分子式: | C22H24N4O4 |
| 分子量: | 408.45 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | Potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM For ROCK-II and ROCK-I respectively).SR-3677 had an IC50 of ~3 nM in enzyme and cell based assays and had an off-target hit rate of 1.4% against 353 kinases, and inhibited only 3 out |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
| TITLE | DOWNLOAD |
| MSDS_3419_DC7246_1072959-67-1 |
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COA
| LOT NO. | DOWNLOAD |
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