APY0201
产品编号: DC7922
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应用领域
APY0201 是一种有效的 PIKfyve 抑制剂，抑制 PtdIns3P 转化为PtdIns(3,5)P2，IC50 为 5.2 nM。 APY0201 还抑制 IL-12/IL-23 产生。
| Cas No.: |
1232221-74-7 |
| 名称: |
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| 别名: |
APY 0201 ,APY-0201 ,APY0201 |
| SMILES: |
CC1=CC=CC(=C1)/C=N\NC2=NC3=CC(=NN3C(=C2)N4CCOCC4)C5=CC=NC=C5 |
| 分子式: |
C23H23N7O |
| 分子量: |
413.2 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
APY0201 exerts its inhibitory activity of IL-12/23 production via PIKfyve inhibition. APY0201 inhibited the conversion of PI3P to PI(3,5)P2 in the presence of recombinant human PIKfyve with an IC50 value of 8.9 nM. It is highly selective for PIKfyve compa |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
