| Cas No.: | 1257044-40-8 |
| 名称: | Benzamide, 4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)- |
| 别名: | ABT199, GDC0199，ABT 199,GDC 0199,GDC-0199 |
| SMILES: | CC1(CCC(=C(C1)C2=CC=C(C=C2)Cl)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)NS(=O)(=O)C5=CC(=C(C=C5)NCC6CCOCC6)[N+](=O)[O-])OC7=CN=C8C(=C7)C=CN8)C |
| 分子式: | C45H50ClN7O7S |
| 分子量: | 868.44 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
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| References: | ABT-199 is a potent and selective inhibitor of B-cell lymphoma-2 (BCL-2) family proteins, currently in clinical trials. It is an engineered version of ABT-263 (Navitoclax) but with much better selectivity. It selectively hits Bcl-2 while ABT-263 hits both Bcl-2 and Bcl-xl. For the detailed information about the solubility of ABT-199 (GDC-0199) in water, the solubility of ABT-199 (GDC-0199) in DMSO, the solubility of ABT-199 (GDC-0199) in PBS buffer, the animal experiment（test） of ABT-199 (GDC-0199),the in vivo,in vitro and clinical trial test of ABT-199 (GDC-0199),the cell experiment（test） of ABT-199 (GDC-0199),the IC50, EC50 and Affinity of ABT-199 (GDC-0199), please contact DC Chemicals. |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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