| Cas No.: | 1337531-36-8 |
| 名称: | 7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyrimidin-4-amine |
| 别名: | GSK2606414,GSK-2606414,GSK 2606414 |
| SMILES: | C1=CC(C2C3C(N)=NC=NC=3N(C)C=2)=CC2CCN(C(=O)CC3=CC=CC(C(F)(F)F)=C3)C1=2 |
| 分子式: | C24H20F3N5O |
| 分子量: | 451.44 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
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| References: | GSK2606414 inhibits PERK Autophosphorylation in A459 Cells with IC50 of <0.3 μM. GSK2606414 exhibits high oral availability, and low to moderate blood clearance in mouse, rat, and dog. GSK2606414, administered orally, inhibits tumor growth in a dose-depe |
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