Mutant IDH1-IN-1
产品编号: DC7982
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应用领域
Mutant IDH1-IN-1是 IDH1 突变体的选择性抑制剂，对突变体IDH1 R132C/R132C，IDH1 R132H/R132H，IDH1 R132H/WT和野生型IDH1的 IC50 值分别为4, 42, 80 和 143 nM。
| Cas No.: |
1355326-21-4 |
| 名称: |
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| 别名: |
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| SMILES: |
CC1=CC=CC=C1C(N(C(CN2C=NC3=CC=CC=C32)=O)C4=CC=CC(F)=C4)/C(O)=N/C5CCCCC5 |
| 分子式: |
C30H31FN4O2 |
| 分子量: |
498.59 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
Mutant IDH1-IN-1 is a potent mutant IDH1 R132H inhibitor with IC50 < 0.1 uM(A level in Patent); more bioactivity information in Patent WO2012009678A1(Example 135). For the detailed information of Mutant IDH1-IN-1, the solubility of Mutant IDH1-IN-1 in wat |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_2057_DC7982_1355326-21-4 |
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COA
| LOT NO. |
DOWNLOAD |
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询盘
