AGI-5198
产品编号: DC5050
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应用领域
AGI-5198是有效和选择性的突变体 IDH1R132H 抑制剂，IC50 为0.07 μM。
| Cas No.: |
1355326-35-0 |
| 名称: |
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| 别名: |
IDH-C35,AGI5198,AGI 5196 |
| SMILES: |
CC1=CC=CC=C1C(C(=O)NC2CCCCC2)N(C3=CC(=CC=C3)F)C(=O)CN4C=CN=C4C |
| 分子式: |
C27H31FN4O2 |
| 分子量: |
462.56 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
AGI-5198(IDH C35) is a novel R132H-IDH1 inhibitor, identified through a high-throughput screen blocked R132H-IDH1 activity in a dose-dependent manner.
IC50 Value:
The ability of the mutant enzyme (mIDH1) to produce R-2-hydroxyglutarate (R-2HG). The recent |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1412_DC5050_1355326-35-0 |
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COA
| LOT NO. |
DOWNLOAD |
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询盘
