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GAL-021

产品编号: DC9859
GAL-021
结构式
1380341-99-0
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中国地区超过5000个高品质化合物库存
应用领域
GAL-021 is a new intravenous BKCa-channel blocker.
Cas No.: 1380341-99-0
名称:
别名: GAL021,GAL 021
SMILES: CCCNC1=NC(N(OC)C)=NC(NCCC)=N1
分子式: C11H22N6O
分子量: 254.33
纯度:
保存条件:
Description:
In Vivo:
In Vitro:
References: GAL-021 is a new intravenous BKCa-channel blocker,well tolerated and stimulates ventilation in healthy volunteers. GAL-021 was safe and generally well tolerated with adverse events comparable with placebo except for an infusion site burning sensation. GAL-021 stimulated ventilation at the highest doses suggesting that greater infusion rates may be required for maximum PD effects. GAL-021 had PK characteristics consistent with an acute care medication.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC9859 GAL-021 GAL-021 is a new intravenous BKCa-channel blocker.
DC9600 Senicapoc Senicapoc(ICA17043) is a potent and selective Gardos channel blocker; blocked Ca(2+)-induced rubidium flux from human RBCs/ inhibited RBC dehydration with IC50s of 11 nM/30 nM, respectively. IC50 value: 11/30 nM [1] Target: Gardos channel in vitro: I