| Cas No.: | 1612888-66-0 |
| 名称: | 3-[[[4-Methyl-2-nitro-5-(3-pyridinyl)phenyl]amino]sulfonyl]benzoic acid |
| 别名: | RPT-835;RPT835;RPT 835;ES 000835 |
| SMILES: | C(O)(=O)C1=CC=CC(S(NC2=CC(C3=CC=CN=C3)=C(C)C=C2[N+]([O-])=O)(=O)=O)=C1 |
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| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
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| References: | Alofanib ((RPT-835, ES 000835) is a potent, selective, allosteric FGFR2 inhibitor that significantly inhibits bFGF-induced proliferation of HUVEC cells with IC50 of 11 nM; suppresses proliferation of SVEC-4-10 cells with IC50 of 58 nM, inhibits growth of FGFR2-expressing SKOV3 cells with GI50 of 0.37 uM; inhibits experimental FGF-induced angiogenesis in vivo. |
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MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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