VR23

产品编号: DC8448 Featured
VR23
结构式
1624602-30-7
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中国地区超过5000个高品质化合物库存
应用领域
VR23有效抑制胰蛋白酶样蛋白酶 (IC50=1nM), 胰凝乳蛋白酶样蛋白酶 (IC50=50-100 nM), 和caspase样蛋白酶 (IC50=3 μM)。
Cas No.: 1624602-30-7
名称:
别名: VR-23,VR 23
SMILES: N1C2C(=CC=C(Cl)C=2)C(N2CCN(S(C3=CC=C([N+]([O-])=O)C=C3[N+]([O-])=O)(=O)=O)CC2)=CC=1
分子式: C19H16ClN5O6S
分子量: 477.88
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: VR23, shows strong potential as a next generation proteasome inhibitor, inhibiting tumor growth as a single agent. Furthermore, when used in combination with gold-standard anticancer drugs, VR23 can increase efficacy while reducing toxicity. VR23 also shows significant potential in overcoming drug resistance. For the detailed information of VR23, the solubility of VR23 in water, the solubility of VR23 in DMSO, the solubility of VR23 in PBS buffer, the animal experiment (test) of VR23, the cell expriment (test) of VR23, the in vivo, in vitro and clinical trial test of VR23, the EC50, IC50,and affinity,of VR23, For the detailed information of VR23, the solubility of VR23 in water, the solubility of VR23 in DMSO, the solubility of VR23 in PBS buffer, the animal experiment (test) of VR23, the cell expriment (test) of VR23, the in vivo, in vitro and clinical trial test of VR23, the EC50, IC50,and affinity,of VR23, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DCAPI1155 Celastrol Tripterin (Celastrol) 是一种蛋白酶体抑制剂,有效且优先抑制20S 蛋白酶体的胰凝乳蛋白酶样活性,IC50 为2.5 μM。
DC8448 VR23 VR23有效抑制胰蛋白酶样蛋白酶 (IC50=1nM), 胰凝乳蛋白酶样蛋白酶 (IC50=50-100 nM), 和caspase样蛋白酶 (IC50=3 μM)。
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