| Cas No.: | 1628502-91-9 |
| 名称: | 6-(4-methylpiperazin-1-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyridazine |
| 别名: | MW01-18-150SRM;MW 150;MW150 |
| SMILES: | C(C1=CC=C2C(=C1)C=CC=C2)1=NN=C(N2CCN(C)CC2)C=C1C1C=CN=CC=1 |
| 分子式: | |
| 分子量: | |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | A novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM; effectively suppresses hippocampal-dependent associative and spatial memory deficits in synaptic dysfunction mouse models; also can selectively modulate neuroinflammatory responses associated with pathology progression. |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |




