NQDI-1
产品编号: DC8787
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应用领域
NQDI-1 抑制凋亡信号调节激酶 1 (ASK1)，Ki 为 500 nM，IC50 为 3 μM。
| Cas No.: |
175026-96-7 |
| 名称: |
2,7-dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid, ethyl ester |
| 别名: |
NQDI-1,NQDI 1,NQDI1 |
| SMILES: |
O=C(C1=C2C(N3)=CC=C1)C4=CC=CC=C4C2=C(C(OCC)=O)C3=O |
| 分子式: |
C19H13NO4 |
| 分子量: |
319.3 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
NQDI-1 is a specific inhibitor of ASK1 (IC50 = 3 μM; Ki = 500 nM) that demonstrates potent selectivity against various serine/threonine and tyrosine protein kinases. It has been used to promote survival of induced pluripotent stem cell populations and to protect neurons from reactive oxygen species-induced apoptosis in a model of ischemia. |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_2485_DC8787_175026-96-7 |
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COA
| LOT NO. |
DOWNLOAD |
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