| Cas No.: | 2307249-33-6 |
| 名称: | (2-amino-4-(trifluoromethoxy)phenyl)(4-(7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl)piperidin-1-yl)methanone |
| 别名: | BAY885 |
| SMILES: | C(C1=CC=C(OC(F)(F)F)C=C1N)(N1CCC(C2N=CN=C3C=C(N4CCN(C)CC4)C=NC3=2)CC1)=O |
| 分子式: | C25H28F3N7O2 |
| 分子量: | 515.541 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | BAY-885 (BAY885) is a highly potent, selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM, shows high selectivity over a panel of 357 kinases (Eurofins panel); strongly inhibits EGF-stimulated MEF2 transcriptional activity in MEF2 reporter assay with IC50 |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
|
|
|
| 2018-0101 |
|
