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In vitro, Tauroursodeoxycholate shows protective and reversing effects on 17βEG-induced impairment of the cVA-of-CLF. In Mz-ChA-1 cholangiocarcinoma cells, Tauroursodeoxycholate inhibits cell growth via Ca2+-, PKC-, and MAPK-dependent pathways. In isolated rat hepatocytes, Tauroursodeoxycholate inhibits bile acid-Induced Apoptosis via a β1-integrin-mediated formation of cAMP. In phalloidin-induced cholestasis rats, Tauroursodeoxycholate (360 μmol/kg, i.v.) significantly suppresses the decrease in bile flow and increases in serum alkaline phosphatase, leucine aminopeptidase and glutamic pyruvic transaminase activities, cholesterol, phospholipid and bile acid concentrations. For the detailed information of Sodium Tauroursodeoxycholate (TUDC), the solubility of Sodium Tauroursodeoxycholate (TUDC) in water, the solubility of Sodium Tauroursodeoxycholate (TUDC) in DMSO, the solubility of Sodium Tauroursodeoxycholate (TUDC) in PBS buffer, the animal experiment (test) of Sodium Tauroursodeoxycholate (TUDC), the cell expriment (test) of Sodium Tauroursodeoxycholate (TUDC), the in vivo, in vitro and clinical trial test of Sodium Tauroursodeoxycholate (TUDC), the EC50, IC50,and affinity,of Sodium Tauroursodeoxycholate (TUDC), For the detailed information of Sodium Tauroursodeoxycholate (TUDC), the solubility of Sodium Tauroursodeoxycholate (TUDC) in water, the solubility of Sodium Tauroursodeoxycholate (TUDC) in DMSO, the solubility of Sodium Tauroursodeoxycholate (TUDC) in PBS buffer, the animal experiment (test) of Sodium Tauroursodeoxycholate (TUDC), the cell expriment (test) of Sodium Tauroursodeoxycholate (TUDC), the in vivo, in vitro and clinical trial test of Sodium Tauroursodeoxycholate (TUDC), the EC50, IC50,and affinity,of Sodium Tauroursodeoxycholate (TUDC), Please contact DC Chemicals. |
