| Cas No.: | 285986-31-4 |
| 名称: | |
| 别名: | Stat5 Inhibitor |
| SMILES: | C1=CC=C2C(=C1)C(=O)C(=CO2)/C=N/NC(=O)C3=CN=CC=C3 |
| 分子式: | C16H11N3O3 |
| 分子量: | 293.28 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | Stat5 Inhibitor is a cell permeable nonpetidic nicotinoyl hydrazone which suppresses Stat5 via binding to the SH2 domain. Studies indicate that Stat5 Inhibitor suppresses the SH2 domain of Stat1 and Stat3 to a lesser extent than Stat5 inhibition. In addition, Stat5/Stat5 DNA binding in K562 nuclear extracts are inhibited by Stat5 Inhibitor. Stat5 functions biologically in various processes such as homeostasis of hematopoietic stem cells, development of blood cells, growth hormone effects, and differentiation of mammary epithelium. |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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