| Cas No.: | 307538-42-7 |
| 名称: | |
| 别名: | SMER-28,SMER 28 |
| SMILES: | C=CCNC1=NC=NC2=C1C=C(C=C2)Br |
| 分子式: | C11H10BrN3 |
| 分子量: | 264.1 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | SMER28 is a small-molecule enhancer (SMER) of autophagy, inducing autophagy independently of rapamycin in mammalian cells when supplied at 47 µM.It increases autophagosome synthesis and enhances clearance of aggregate-prone substrates, including those relevant to Huntington’s, Parkinson’s, and Alzheimer’s diseases.SMER28 promotes reprogramming of fibroblasts into neural stem cells when used in combination with other chemical reagents. |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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