Toceranib(SU 11654; PHA 291639)
产品编号: DC7329
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应用领域
Toceranib phosphate (SU11654 phosphate) 是一种口服活性受体酪氨酸激酶 (RTK) 抑制剂，能有效抑制PDGFR，VEGFR，Kit，抑制 PDGFRβ 和 Flk-1/KDR 的 Ki 值分别为 5 nM 和 6 nM。Toceranib phosphate (SU11654 phosphate) 具有抗肿瘤和抗血管生成活性，用于犬肥大细胞肿瘤的治疗。
| Cas No.: |
356068-94-5 |
| 名称: |
5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide |
| 别名: |
SU 11654; PHA 291639; SU11654; SU-11654; PHA-291639; PHA291639 |
| SMILES: |
CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)/C=C\3/C4=C(C=CC(=C4)F)NC3=O |
| 分子式: |
C22H25FN4O2 |
| 分子量: |
396.457903 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
Toceranib ( Formerly known as SU11654) is a receptor tyrosine kinase inhibitor and is used in the treatment of canine mast cell tumor also called mastocytoma. Toceranib is the only dog-specific anti-cancer drug approved by the U.S. Food and Drug Administ |
| Kinase Assay: |
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| Animal Administration: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
