AZD2932
产品编号: DC7799
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应用领域
AZD2932是有效的多靶点激酶抑制剂，细胞试验中的抑制VEGFR2，PDGFβ，PDGFβ 和 PDGFβ 的 IC50 值分别为8，4，7，9 nM。
| Cas No.: |
883986-34-3 |
| 名称: |
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| 别名: |
AZD 2932, AZD-2932, AGN-PC-00AQ5T,AZD2932 |
| SMILES: |
C(NC1=CN(C(C)C)N=C1)(=O)CC1=CC=C(OC2=C3C(=NC=N2)C=C(OC)C(OC)=C3)C=C1 |
| 分子式: |
C24H25N5O4 |
| 分子量: |
447.486 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
AZD-2932 is a high affinity inhibitor of VEFGR-2 and PDGFR. AZD-2932 has a balanced ~1:1 ratio of activity vs both VEGFR-2 and PDGFRβ and shows IC50 values of 8 and 4 nM against the two enzymes, respectively. It is also active on c-Kit and FLT3 with good |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1968_DC7799_883986-34-3 |
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COA
| LOT NO. |
DOWNLOAD |
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