Preladenant(SCH420814)
产品编号: DC9805
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应用领域
Preladenant 是一种有效，竞争性的人腺苷 A2A 受体拮抗剂，Ki 为 1.1 nM，比其他腺苷受体选择性高100倍以上。
| Cas No.: |
377727-87-2 |
| 名称: |
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| 别名: |
SCH-420814; SCH 420814; SCH420814 |
| SMILES: |
COCCOC1=CC=C(C=C1)N2CCN(CC2)CCN3C4=C(C=N3)C5=NC(=NN5C(=N4)N)C6=CC=CO6 |
| 分子式: |
C25H29N9O3 |
| 分子量: |
503.56 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
The adenosine A(2A) receptor has been implicated in the underlying biology of various neurological and psychiatric disorders, including Parkinson's disease (PD) and depression. Preladenant is being researched as a potential treatment for Parkinson's disease. Positive results were reported in Phase II clinical trials in humans. |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
