Pazopanib

产品编号: DC2600 Featured
Pazopanib
结构式
444731-52-6
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中国地区超过5000个高品质化合物库存
应用领域
Pazopanib (GW786034) 是多靶点抑制剂,抑制 VEGFR1,VEGFR2,VEGFR3,PDGFRβ,c-Kit,FGFR1,c-Fms的IC50分别为10,30,47,84,74,140,146 nM。
Cas No.: 444731-52-6
名称: 5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide
别名: Votrient
SMILES: CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N
分子式: C21H23N7O2S
分子量: 437.52
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Pazopanib hydrochloride is an approved drug, is the hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). For the detailed information about the solubility of Pazopanib in water, the solubility of Pazopanib in DMSO, the solubility of Pazopanib in PBS buffer, the animal experiment(test) of Pazopanib,the in vivo,in vitro and clinical trial test of Pazopanib,the cell experiment(test) of Pazopanib,the IC50, EC50 and Affinity of Pazopanib, please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
TITLE DOWNLOAD
MSDS_1259_DC2600_444731-52-6
COA
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产品编号 产品名称 应用领域
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