NU-7441 (KU-57788)
产品编号: DC3100
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应用领域
KU-57788 是一种有效的，选择性的 DNA-PK 抑制剂，IC50 值为 13 nM。
| Cas No.: |
503468-95-9 |
| 名称: |
4H-1-Benzopyran-4-one, 8-(4-dibenzothienyl)-2-(4-morpholinyl)- |
| 别名: |
NU7441，KU57788,NU 7441 (KU 57788) |
| SMILES: |
C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56 |
| 分子式: |
C25H19NO3S |
| 分子量: |
413.49 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
Potent and selective DNA-PK inhibitor (IC50 = 14 nM). Selective for DNA-PK over a range of kinases including mTOR, PI 3-K, ATM and ATR. Potentiates the effects of doxorubicin and etoposide in vitro and etoposide in vivo. Also enhances CRISPR-Cas9-mediated |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1320_DC3100_503468-95-9 |
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COA
| LOT NO. |
DOWNLOAD |
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询盘
