| References: |
A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.A-77-01 is a close analogue of A-83-01(Axon 1421) and has a very similar biological profile of A-83-01. A-83-01 is found to decompose to A-77-01 under certain circumstances and A-77-01 is likely an active component or metabolite of its prodrug A-83-01.
For the detailed information of A77-01, the solubility of A77-01 in water, the solubility of A77-01 in DMSO, the solubility of A77-01 in PBS buffer, the animal experiment (test) of A77-01, the cell expriment (test) of A77-01, the in vivo, in vitro and clinical trial test of A77-01, the EC50, IC50,and affinity,of A77-01, Please contact DC Chemicals. |
