Barasertib (AZD1152-HQPA)
产品编号: DC1029
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应用领域
Barasertib-HQPA (AZD2811) 是一种高度选择性的极光激酶B抑制剂，在非细胞试验中 IC50 值为0.37 nM。Barasertib-HQPA (AZD2811) 对Aurora B 的选择性是Aurora A的3700倍。
| Cas No.: |
722544-51-6 |
| 名称: |
2-(5-(7-(3-(ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-ylamino)-1H-pyrazol-3-yl)-N-(3-fluorophenyl)acetamide |
| 别名: |
AZD1152, AZD-1152 |
| SMILES: |
CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCO |
| 分子式: |
C26H30FN7O3 |
| 分子量: |
507.56 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
Description of AZD-1152HQPA: AZD-1152HQPA is an active metabolite of Barasertib (AZD-1152), which is a novel acetanilide-substituted pyrazole-aminoquinazoline prodrug that is converted rapidly to the active drug AZD-1152 hydroxy-QPA (AZD1152-HQPA) in huma |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_170_DC1029_722544-51-6 |
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COA
| LOT NO. |
DOWNLOAD |
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