STF-31

产品编号: DC8359 Featured
STF-31
结构式
724741-75-7
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中国地区超过5000个高品质化合物库存
应用领域
STF-31 是一种葡萄糖转运1抑制剂 (GLUT1, IC50 = 1 μM)。
Cas No.: 724741-75-7
名称: 4-[[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinyl-benzamide
别名: STF31,STF 31
SMILES: C(NC1=CC=CN=C1)(=O)C1=CC=C(CNS(C2=CC=C(C(C)(C)C)C=C2)(=O)=O)C=C1
分子式: C23H25N3O3S
分子量: 423.5
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: STF-31 is an inhibitor of GLUT1 (IC50 = ~1 µM) that blocks glucose uptake.It induces necrosis in cancer cells that lack the von Hippel-Lindau tumor suppressor gene, which overexpress GLUT1.Although STF-31 binds GLUT1, suggesting a direct effect, STF-31 also inhibits nicotinamide phosphoribosyltransferase, an enzyme that induces GLUT1 expression. STF-31 is also toxic to human pluripotent stem cells (hPSCs) and can be used to selectively eliminate hPSCs from mixed cultures. For the detailed information of STF-31, the solubility of STF-31 in water, the solubility of STF-31 in DMSO, the solubility of STF-31 in PBS buffer, the animal experiment (test) of STF-31, the cell expriment (test) of STF-31, the in vivo, in vitro and clinical trial test of STF-31, the EC50, IC50,and affinity,of STF-31, For the detailed information of STF-31, the solubility of STF-31 in water, the solubility of STF-31 in DMSO, the solubility of STF-31 in PBS buffer, the animal experiment (test) of STF-31, the cell expriment (test) of STF-31, the in vivo, in vitro and clinical trial test of STF-31, the EC50, IC50,and affinity,of STF-31, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
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MSDS_2304_DC8359_724741-75-7
COA
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产品编号 产品名称 应用领域
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