GNF-2

产品编号: DC1062 Featured
GNF-2
结构式
778270-11-4
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中国地区超过5000个高品质化合物库存
应用领域
GNF-2是非ATP竞争性的Bcr-Abl选择性抑制剂,IC50为140nM。
Cas No.: 778270-11-4
名称: Benzamide, 3-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-
别名: GNF2,GNF 2
SMILES: C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F
分子式: C18H13F3N4O2
分子量: 374.32
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Description of GNF-2: GNF-2 is an allosteric inhibitor of Bcr-abl tyrosine kinase activity (IC50 = 267 nM); inhibits proliferation and induces apoptosis in Bcr-abl-expressing cells. Selective For Bcr-abl over a panel of serine, threonine and tyrosine kinases. Non-ATP-competitive. For the detailed information about the solubility of GNF-2 in water, the solubility of GNF-2 in DMSO, the solubility of GNF-2 in PBS buffer, the animal experiment(test) of GNF-2,the in vivo,in vitro and clinical trial test of GNF-2,the cell experiment(test) of GNF-2,the IC50, EC50 and Affinity of GNF-2, please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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DC1062 GNF-2 GNF-2是非ATP竞争性的Bcr-Abl选择性抑制剂,IC50为140nM。