Obicetrapib (AMG-899,TA-8995)

产品编号: DC10134
Obicetrapib (AMG-899,TA-8995)
结构式
866399-87-3
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中国地区超过5000个高品质化合物库存
应用领域
Obicetrapib is a CETP inhibitor, on the elevation of high-density lipoprotein cholesterol (HDL-C) and reduction of low-density lipoprotein cholesterol (LDL-C), alone and in combination with statin therapy.
Cas No.: 866399-87-3
名称: 4-((2-((3,5-bis(trifluoromethyl)benzyl)((2R,4S)-1-(ethoxycarbonyl)-2-ethyl-6-
别名: AMG 899,TA 8995,AMG899,TA8995,
SMILES: O=C(O)CCCOC1=CN=C(N(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)[C@H]3C[C@@H](CC)N(C(OCC)=O)C4=C3C=C(C(F)(F)F)C=C4)N=C1
分子式: C32H31F9N4O5
分子量: 722.6
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Obicetrapib (also known as AMG-899, TA-8995, and DEX-001) is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial effect for cardiovascular disease risk reduction.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
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MSDS_3328_DC10134_866399-87-3
COA
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产品编号 产品名称 应用领域
DC10134 Obicetrapib (AMG-899,TA-8995) Obicetrapib is a CETP inhibitor, on the elevation of high-density lipoprotein cholesterol (HDL-C) and reduction of low-density lipoprotein cholesterol (LDL-C), alone and in combination with statin therapy.